Incyte, the Delaware-based pharmaceutical research firm, has joined the S&P 500 Index.
The index includes the most-owned stocks on the New York Stock Exchange and Nasdaq, the two largest exchanges in the United States.
Incyte pushed out Spectra Energy Corp, a natural gas company in the midst of an acquisition by Enbridge.
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There are now two Delaware-based companies on the S&P 500, including DuPont and now Incyte.
The company recently reported a profitable 2016, in part due to sales of its cancer-treating drug Jakafi.
